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Last updated: May 31, 2024The adrenal washout calculator estimates adrenal washout using a non-contrast scan, a contrast-enhanced scan with a delay of 60-75 seconds, and a delayed scan at 15 minutes. We use it primarily to diagnose adrenal adenoma.If you find this calculator helpful, then check out our other nephrology tools. With the GFR calculator you can find the glomerular filtration rate to diagnose kidney malfunction, and the FENa calculator can help you establish the cause of acute kidney failure.We try our best to make our Omni Calculators as precise and reliable as possible. However, this tool can never replace a professional doctor's assessment.The adrenal washout calculatorAdenomas (both lipid-rich and lipid-poor) rapidly wash out contrast, whereas non-adenomas (e.g., metastases) generally enhance quickly but take longer to washout. Therefore, you can use the adrenal washout formula to distinguish adrenal adenomas from non-adenomas.Adrenal washout protocol consists of three elements:A non-contrast scan;A contrast-enhanced scan with a delay of 60-75 seconds; andA delayed scan at 15 minutes.Interpretation and characteristic:Absolute washout higher than 60% is highly suggestive of an adrenal adenoma;Relative washout higher than 40% is highly suggestive of an adrenal adenoma;Any adrenal lesion higher than 120 HU (Hounsfield Unit) with washout should not be diagnosed as an adenoma;Pheochromocytomas may also wash out, however the presence of intracytoplasmic lipid in pheochromocytomas (In patients with renal cell carcinoma, hepatocellular carcinoma (and other tumors with hypervascular metastases) washout measurements may have significantly reduced specificity;A non-calcified, non-hemorrhagic lesion with pre-contrast HU higher than 43 is suspicious for malignancy, regardless of the washout value; andWashout characteristics should not be used to diagnose inhomogeneous lesions with large areas of necrosis or hemorrhage.Adrenal washout formulaThere are two Adrenal washout formulas:Absolute = 100 × [(post HU - delayed HU)/(post HU - pre HU)] andRelative = 100 × [(post HU - delayed HU)/post

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